Objective: The efficacy of Ji Desheng snake pills combined with hypertonic\nglucose external application in treating drug-induced superficial phlebitis\ncaused by parenteral nutrition (PN) is observed. Methods: Fifty-two cases of\ndrug-induced superficial phlebitis after peripheral parenteral nutrition (PPN)\nwere selected, which were randomly divided into experimental group and\ncontrol group in accordance with the phlebitis grading. In the experimental\ngroup, Ji Desheng snake pills were crushed to make a paste with 50% glucose\nsolution, which was then applied to the affected area of phlebitis, the surface\nwas covered with clean gauze, and properly fixed with tape or bandage. The\ndrug was replaced once a day. In the control group, the gauze soaked with\n50% magnesium sulfate solution was used, which was applied to the affected\npart three times a day in wet, and the efficacy was observed respectively on the\n1st, 3rd, 5th and 7th days after applying the drug. Results: On the 1st and 3rd days\nafter treatment, the observed effective rate of the experimental group was\nhigher than that of the control group (42.31% vs. 15.38% and 76.92% vs.\n46.15%, respectively). The difference was statistically significant (p < 0.05). In\nterms of the effective rate observed on the 5th and 7th days after treatment,\nthere was no statistical significance with respect to the efficacy between the\nexperimental group and the control group (p > 0.05). Conclusion: The significant\nefficacy could be found in early stage after drug-induced superficial\nphlebitis was treated by Ji Desheng snake pills combined with hypertonic glucose\nexternal application, which was superior to that of the traditional treatment\nof wet application by using gauze soaked in 50% magnesium sulfate solution.
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